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This Concept Map, created with IHMC CmapTools, has information related to: Answers_viral latency, Certain viruses that infect humans establish persistent infection by using their own miRNAs and/or miRNAs produced by their human host. examples herpes viruses, cytomegalovirus (CMV) causes a variety of infections in immunosuppressed persons; also a leading cause of birth defect, chicken pox and shingles latent in sensory neurons, RNA interference (RNAi) where small non-coding regulatory RNAs such as microRNAs (miRNAs) regulate gene expression. ???? Certain viruses that infect humans establish persistent infection by using their own miRNAs and/or miRNAs produced by their human host., herpes viruses ???? herpes simplex-1 virus (HSV-1), herpes viruses ???? herpes simplex-2 virus (HSV-2), HIV causes HIV infection, AIDS, herpes simplex-1 virus (HSV-1) causes most oral herpes (cold sores), most oral herpes (cold sores) latent in sensory neurons, RNA interference (RNAi) where small non-coding regulatory RNAs such as microRNAs (miRNAs) regulate gene expression. bind to viral mRNA Viral and/or host miRNAs may bind to certain viral messenger RNA (mRNA) molecules and block translation of viral proteins required for rapid viral replication, infectious mononucleosis latent in B-lymphocytes, most genital herpes latent in sensory neurons, Certain viruses that infect humans establish persistent infection by using their own miRNAs and/or miRNAs produced by their human host. examples retroviruses, herpes viruses ???? varicella-zoster virus (VZV), RNA interference (RNAi) where small non-coding regulatory RNAs such as microRNAs (miRNAs) regulate gene expression. bind to host cell mRNA miRNAs may directly affect host immune defenses by turning off the production of antiviral cytokines or by blocking apoptosis of infected host cells., herpes simplex-2 virus (HSV-2) causes most genital herpes, viral latency definition An infection that does not immediately produce detectable symptoms. Viral replication is at low levels., retroviruses ???? HIV, varicella-zoster virus (VZV) causes chicken pox and shingles, viral latency due to RNA interference (RNAi) where small non-coding regulatory RNAs such as microRNAs (miRNAs) regulate gene expression.